ANTIULCEROGENIC BENEFITS OF HERBAL INGREDIENTS IN ETHANOL-INDUCED ANIMAL MODELS

African Journal of Traditional, Complementary and Alternative Medicines · Volume 13, Issue 2 (2016) · pp. 1–24

DOI: 10.21010/ajtcam.v13i2.1

Abstract

<jats:p>pathogenesis of gastric ulcer. Although therapeutic approaches are widely available, preventive regimens are limited. Numerous studies&#x0D;
have demonstrated that herbal medicines display preventive benefit in the development of ethanol-induced gastric ulcers in both rat and&#x0D;
mouse models. The preventive efficacy of herbal medicines on the development of ethanol-induced gastric ulcers is comparable or&#x0D;
superior to histamine receptor 2 antagonists. But herbal medicines have fewer side effects.&#x0D;
Materials and Methods: Keywords including gastric ulcer, herbal medicines, prevention and natural ingredients were used to search&#x0D;
on http://www.ncbi.nlm.nih.gov/pubmed. The search was performed on January 12, 2014. Only articles published in English were used&#x0D;
in this review.&#x0D;
Result and Conclusion: According to the mechanisms of their action and pathogenesis of gastric ulcer, combination of certain herbal&#x0D;
medicines could be a valuable alternative to prevent the development of gastric ulcer, particularly for the subjects who are at a higher risk&#x0D;
of developing gastric ulcer.</jats:p>